Correlative microscopy of single self-assembled nanorod dimers for refractometric sensing

Michael A. Beuwer, Peter Zijlstra* Single metallic particles and dimers of nanospheres have been used extensively for sensing, but dimers of particles provide attractive advantages because they exhibit multiple modes that can be tuned by the dimer geometry. Here, we employ correlative microscopy of single self-assembled dimers of gold nanorods to study their performance as […]

Imaging and Localization of Single Emitters near Plasmonic Particles of Different Size, Shape, and Material

Frank Bloksma, Peter Zijlstra* Colloidal plasmonic materials are increasingly used in biosensing and catalysis, which has sparked the use of super-resolution localization microscopy to visualize processes at the interface of the particles. We quantify the effect of particle–emitter coupling on super-resolution localization accuracy by simulating the point spread function (PSF) of single emitters near a […]

PhD vacancy available

We are excited to announce that a PhD vacancy is available for application at the molecular plasmonics group in Eindhoven University of Technology. PhD position on single-molecule plasmon sensing The PhD student will develop single-molecule and continuous biosensing principles based on plasmonic nanoparticles and optical detection methods. The project involves the design of plasmonic sensing […]

Researcher vacancies available

We are happy to announce that we are currently hiring 3 scientists to join our team! We are constantly seeking to use our fantastic molecular plasmonics tools to answer intriguing biophysical questions. If you are an enthusiastic individual that shares our vision, please don’t hesitate to apply for the following positions: PhD position on protein-nanoparticle […]

Research paper published in JPC Letters

DOI: doi.org/10.1021/acs.jpclett.0c00155 Yuyang Wang, Matěj Horáček, and Peter Zijlstra Plasmon resonances have appeared as a promising method to boost the fluorescence intensity of single emitters. However, because research has focused on the enhancement at low excitation intensity, little is known about plasmon–fluorophore coupling near the point where the dye saturates. Here we study plasmon-enhanced fluorescence […]

Research paper published in Nanoscale

Dynamic single-molecule counting for the quantification and optimization of nanoparticle functionalization protocols DOI: doi.org/10.1039/C9NR10218C Matěj Horáček,  Dion J. Engels, Peter Zijlstra Applications of colloidal particles in the fields of i.e. biosensors, molecular targeting, or drug-delivery require their functionalization with biologically active and specific molecular ligands. Functionalization protocols often result in a heterogeneous population of particles with a […]

Two PhD vacancies available (filled)

These positions have been filled. We are excited to announce that two PhD vacancies are available for application at the molecular plasmonics group in Eindhoven University of Technology. PhD position on correlative super-resolution microscopy of nanoparticles (V34.4269) PhD position on responsive nanoplasmonic sensors (V34.4270) The two PhD positions are supported by The SuperCol Innovative Training […]

Gold particle shines like a flashlight on proteins

Original post can be found on the TU/e website. Peter Zijlstra recently received a Consolidator Grant of € 2 million from the European Research Council (ERC). He is using the grant for his research into making protein interactions visible by means of gold particles. In this way he hopes to be able to unravel how […]